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20665 1 ap anti synapsin i primary  (Proteintech)


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    Structured Review

    Proteintech 20665 1 ap anti synapsin i primary
    20665 1 Ap Anti Synapsin I Primary, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 452 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/synapsin+i/PSD95-Specific%2CDLG4+Antibody/pm41933661-135-9-8
    Average 96 stars, based on 452 article reviews
    20665 1 ap anti synapsin i primary - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    Incubation:

    Article Title: Young plasma reverses anesthesia and surgery-induced cognitive impairment in aged rats by modulating hippocampal synaptic plasticity.
    Article Snippet: The samples were blocked in PBS containing 0.3% Triton X-100 (Sigma-Aldrich, Munich, Germany) and 5% bovine serum album (Beyotime, Beijing, China) for 2 h at room temperature. .. The samples were then incubated with synapsin-I (Proteintech, 1:100, Cat No. 17785-1- AP), p-CREB (Cell Signaling Technology, 1:100, Cat. no. 9198S), and Neun (Proteintech, 1:100, Cat No. 26975-1-AP) overnight at 4◦C. .. The sections were washed three times with PBS before being incubated for 1 h with a goat anti-rabbit immunoglobulin G-FITC secondary antibody (1:100, Beyotime, P0186).

    Ubiquitin Proteomics:

    Article Title: The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
    Article Snippet: .. The following primary antibodies were used in this study: GFP (Proteintech, 66002-1-Ig), Sup35 (Abnoca, PAB15578), glyceraldehyde phosphate dehydrogenase (Proteintech, 60004-1-Ig), phospho–α-Syn (Ser129) (Biolegend, MMS-5091), phospho–α-Syn (Ser129) (Cell Signaling Technology, 23706), synaptophysin (Proteintech, 17785-1-AP), PSD-95 (20665-1-AP), synapsin I (Proteintech, 20258-1-AP), α-syn (syn211, Invitrogen, MA5-12272), glutathione S-transferase (66001-2-Ig), NeuN (Millipore, MAB377), TH (Millipore, AB152), DAT (Abcam, ab184451), ubiquitin (Cell Signaling Technology, 3936S), p62 (Abcam, 56416), Microtuble-associated protein 2 (MAP2) (Proteintech, 17490-1-AP and Invitrogen, 13-1500), tau (Thermo, MA5-12808), Bcl2 (Cell Signaling Technology, 15071), Bax (Abcam, ab32503), Cox IV (Abcam, ab16056), Alexa Fluor 488-Goat anti-Mouse (Invitrogen, A11001), Alexa Fluor 594-Goat anti-Mouse (Invitrogen, A11005), Alexa Fluor 488-Goat anti-Rabbit (Invitrogen, A11034), and Alexa Fluor 594-Goat anti-Rabbit (Invitrogen, A11012). .. DiI (Thermo Fisher Scientific, 1975524).

    Article Title: Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
    Article Snippet: Pathologic aggregation and prion-like propagation of α-synuclein (α-syn) are the hallmarks of Parkinson’s disease (PD).. Emerging evidence shows that type 2 diabetes mellitus (T2DM) is a risk factor for PD.. Interestingly, T2DM is characterized by the amyloid deposition of islet amyloid polypeptide (IAPP) in the pancreas.

    Article Title: CHIP Decline Is Associated With Isoflurane-Induced Neurodegeneration in Aged Mice
    Article Snippet: .. Rabbit antibodies were CHIP (proteintech), synapsin I (SYN I, proteintech), phosphorylated synapsin I S9 (SYN I-S9, Affinity), S427 (SYN I-S427, Affinity), S605 (SYN I-S605, Affinity), ubiquitin (proteintech), SNAP25 (Affinity), and PSD95 (Affinity). ..

    Article Title: The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson’s disease
    Article Snippet: .. The following primary antibodies were used in this study: GFP (Proteintech, 66002-1-Ig), Sup35 (Abnoca, PAB15578), glyceraldehyde phosphate dehydrogenase (Proteintech, 60004-1-Ig), phospho–α-Syn (Ser 129 ) (Biolegend, MMS-5091), phospho–α-Syn (Ser 129 ) (Cell Signaling Technology, 23706), synaptophysin (Proteintech, 17785-1-AP), PSD-95 (20665-1-AP), synapsin I (Proteintech, 20258-1-AP), α-syn (syn211, Invitrogen, MA5-12272), glutathione S -transferase (66001-2-Ig), NeuN (Millipore, MAB377), TH (Millipore, AB152), DAT (Abcam, ab184451), ubiquitin (Cell Signaling Technology, 3936S), p62 (Abcam, 56416), Microtuble-associated protein 2 (MAP2) (Proteintech, 17490-1-AP and Invitrogen, 13-1500), tau (Thermo, MA5-12808), Bcl2 (Cell Signaling Technology, 15071), Bax (Abcam, ab32503), Cox IV (Abcam, ab16056), Alexa Fluor 488-Goat anti-Mouse (Invitrogen, A11001), Alexa Fluor 594-Goat anti-Mouse (Invitrogen, A11005), Alexa Fluor 488-Goat anti-Rabbit (Invitrogen, A11034), and Alexa Fluor 594-Goat anti-Rabbit (Invitrogen, A11012). .. DiI (Thermo Fisher Scientific, 1975524).

    Lysis:

    Article Title: Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway.
    Article Snippet: .. Materials and reagents used in this study were purchased from commercial sources: Human cystatin C kit (item no. ab179883) from Abcam; CysC drug from Enzo Life Sciences; RIPA lysis buffer from Beyotime Biotechnology Co., Ltd.; sucrose, glucose, KCl, NaHCO3, NaH2PO4, CaCl2 and MgCl2 from Sigma‐Aldrich; Merck KGaA; rat brain stereotaxic device from Anhui Zhenghua Biological Instrument Co., Ltd.; primary antibodies to cystatin C (item no. ab109508), p-extracellular signal-regulated kinase 1/2 (ERK1/2) (item no. ab223500), synapsin I (item no. ab8), and p‐synapsinI‐S549 (item no. ab119370) from Abcam; and β-actin primary antibody (item no. 66009-1-Ig) from Proteintech. ..

    Labeling:

    Article Title: Cofilin 1 promotes the aggregation and cell-to-cell transmission of α-synuclein in Parkinson's disease.
    Article Snippet: The histopathological hallmark of Parkinson’s disease (PD) is the presence of fibrillar aggregates referred to as Lewy bodies (LBs), in which a-synuclein is the major component.. Converging evidence supports the prion-like transmission of a-synuclein aggregates in the onset and progression of PD.. Intracellular asynuclein aggregates into pathological fibrils, which can be transferred from aggregate-producing cells to aggregate-free cells, triggering neuronal injury and the progression of pathology.



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    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp , GAP43 , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: <t>synapsin</t> <t>II;</t> Syp: synaptophysin.
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    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp <t>,</t> <t>GAP43</t> , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: <t>synapsin</t> II; Syp: synaptophysin.
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    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp <t>,</t> <t>GAP43</t> , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: <t>synapsin</t> II; Syp: synaptophysin.
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    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp <t>,</t> <t>GAP43</t> , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: <t>synapsin</t> II; Syp: synaptophysin.
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    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp <t>,</t> <t>GAP43</t> , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: <t>synapsin</t> II; Syp: synaptophysin.
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    Image Search Results


    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp , GAP43 , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: synapsin II; Syp: synaptophysin.

    Journal: Neural Regeneration Research

    Article Title: Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway

    doi: 10.4103/NRR.NRR-D-24-00628

    Figure Lengend Snippet: NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp , GAP43 , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: synapsin II; Syp: synaptophysin.

    Article Snippet: In addition, Synapsin I and Synapsin II exert essential roles in neurotransmitter release (Cesca et al., 2010).

    Techniques: Functional Assay

    NRMS alters expression of proteins associated with synaptic plasticity in the injured spinal cord of rats. (A) Representative western blots show the expression levels of PSD95, GAP43, Synapsin I and Synapsin II collected from the damaged area of spinal cord on day 22 after SCI. (B–E) The semi-quantified results of PSD95, GAP43, Synapsin I, and Synapsin II protein levels. All experiments were repeated three times. Data are expressed as mean ± SD ( n = 5 per group). ** P < 0.01, *** P < 0.001, vs. Sham group; # P < 0.05, ## P < 0.01, vs . SCI + SS group. GAP43: Growth-associated protein 43; PSD95: postsynaptic density protein-95; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation.

    Journal: Neural Regeneration Research

    Article Title: Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway

    doi: 10.4103/NRR.NRR-D-24-00628

    Figure Lengend Snippet: NRMS alters expression of proteins associated with synaptic plasticity in the injured spinal cord of rats. (A) Representative western blots show the expression levels of PSD95, GAP43, Synapsin I and Synapsin II collected from the damaged area of spinal cord on day 22 after SCI. (B–E) The semi-quantified results of PSD95, GAP43, Synapsin I, and Synapsin II protein levels. All experiments were repeated three times. Data are expressed as mean ± SD ( n = 5 per group). ** P < 0.01, *** P < 0.001, vs. Sham group; # P < 0.05, ## P < 0.01, vs . SCI + SS group. GAP43: Growth-associated protein 43; PSD95: postsynaptic density protein-95; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation.

    Article Snippet: In addition, Synapsin I and Synapsin II exert essential roles in neurotransmitter release (Cesca et al., 2010).

    Techniques: Expressing, Western Blot

    NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp , GAP43 , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: synapsin II; Syp: synaptophysin.

    Journal: Neural Regeneration Research

    Article Title: Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway

    doi: 10.4103/NRR.NRR-D-24-00628

    Figure Lengend Snippet: NRMS upregulates transcriptional levels of genes related to synaptic plasticity in damaged region of SCI rats. (A) The functional classification of different genes in the SCI + NRMS and SCI + SS groups by GO enrichment analysis. (B) The functional classification of different genes between the SCI + NRMS and SCI + SS groups by KEGG database. (C–F) The relative levels of Syn2 , Syp , GAP43 , and MAP2 mRNA normalized by the Sham group. The bold lines, upper boundaries, and lower boundaries represent the medians, 75 th percentiles, and 25 th percentiles, respectively. Whiskers extend 1.5 times interquartile range ( n = 4 per group). * P < 0.05, vs . Sham group; # P < 0.05, vs . SCI + SS group. GAP43: Growth-associated protein 43; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MAP2: microtubule-associated protein 2; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation; Syn2: synapsin II; Syp: synaptophysin.

    Article Snippet: The following antibodies were used: postsynaptic density protein-95 (PSD95; rabbit, 1:1000, Cell Signaling Technology, Danvers, MA, USA, Cat# 3450S, RRID: AB_2292883), Synapsin I (rabbit, 1:1000, Abmart, Shanghai, China, Cat# 334286), GAP43 (mouse, 1:400, Santa Cruz, Biotechnology, Dallas, TX, USA, Cat# sc-17790, RRID: AB_627660), Synapsin II (rabbit, 1:1000, Abclonal, Wuhan, China, Cat# A19542), and GAPDH (mouse, 1:20 000, Sigma-Aldrich, Cat# G8795, RRID: AB_1078991).

    Techniques: Functional Assay

    NRMS alters expression of proteins associated with synaptic plasticity in the injured spinal cord of rats. (A) Representative western blots show the expression levels of PSD95, GAP43, Synapsin I and Synapsin II collected from the damaged area of spinal cord on day 22 after SCI. (B–E) The semi-quantified results of PSD95, GAP43, Synapsin I, and Synapsin II protein levels. All experiments were repeated three times. Data are expressed as mean ± SD ( n = 5 per group). ** P < 0.01, *** P < 0.001, vs. Sham group; # P < 0.05, ## P < 0.01, vs . SCI + SS group. GAP43: Growth-associated protein 43; PSD95: postsynaptic density protein-95; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation.

    Journal: Neural Regeneration Research

    Article Title: Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway

    doi: 10.4103/NRR.NRR-D-24-00628

    Figure Lengend Snippet: NRMS alters expression of proteins associated with synaptic plasticity in the injured spinal cord of rats. (A) Representative western blots show the expression levels of PSD95, GAP43, Synapsin I and Synapsin II collected from the damaged area of spinal cord on day 22 after SCI. (B–E) The semi-quantified results of PSD95, GAP43, Synapsin I, and Synapsin II protein levels. All experiments were repeated three times. Data are expressed as mean ± SD ( n = 5 per group). ** P < 0.01, *** P < 0.001, vs. Sham group; # P < 0.05, ## P < 0.01, vs . SCI + SS group. GAP43: Growth-associated protein 43; PSD95: postsynaptic density protein-95; NRMS: nerve root magnetic stimulation; SCI: spinal cord injury; SS: sham stimulation.

    Article Snippet: The following antibodies were used: postsynaptic density protein-95 (PSD95; rabbit, 1:1000, Cell Signaling Technology, Danvers, MA, USA, Cat# 3450S, RRID: AB_2292883), Synapsin I (rabbit, 1:1000, Abmart, Shanghai, China, Cat# 334286), GAP43 (mouse, 1:400, Santa Cruz, Biotechnology, Dallas, TX, USA, Cat# sc-17790, RRID: AB_627660), Synapsin II (rabbit, 1:1000, Abclonal, Wuhan, China, Cat# A19542), and GAPDH (mouse, 1:20 000, Sigma-Aldrich, Cat# G8795, RRID: AB_1078991).

    Techniques: Expressing, Western Blot